Nicolas Durand

post-doctorant sur le rôle des toxines issues du venin d’hyménoptères parasitoïdes

Spécialité : Ecophysiologie des insectes

Axe 1

Projet :

L’objectif du projet PARAVETOX, financé par le dispositif START AIIR de la Région Hauts de France (2019-2020), est de mettre en place des protocoles permettant la production de biomolécules extraites du venin d’insectes hyménoptères et de développer des techniques de clonage et d’expression de gènes sur le long terme. Le projet PARAVETOX est basé sur une approche pluridisciplinaire dédiée à l’exploitation de substances biologiques actives ayant potentiellement des effets thérapeutiques.

Publications :

Gassias E, Durand N, Demondion E, Bourgeois T, Aguilar P, Bozzolan F, Debernard S (2019) A critical role for Dop1-mediated dopaminergic signaling in the plasticity of behavioral and neuronal responses to sex pheromone in a moth. J. Exp. Biol. 222: jeb211979

Durand N, Bozzolan F, Chertemps T, Pottier MA, Siaussat D and Maïbèche M (2018) Glutathione-S-transferases in the olfactory organ of the noctuid moth Spodoptera littoralis, diversity and conservation of chemosensory clades. Front.Physiol. 9(1283)

Aviles A, Boulogne I, Durand N, Maria A, Cordeiro A, Bozzolan F, Goutte A, Alliot F, Dacher M, Renault D, Maïbèche M, Siaussat D (2018) Effects of DEHP on post-embryonic development, nuclear receptor expression, metabolite and ecdysteroid concentrations of the moth Spodoptera littoralis. Chemosphere 215: 725-738

Garcias E, Durand N, Demondion E, Bourgeois T, Bozzolan F, Debernard S (2018) The insect HR38 nuclear receptor, a member of the NR4A subfamily, is a synchronizer of reproductive activity in a moth. The FEBS journal 285 (21): 4019-4040

Durand N., Chertemps T., Bozzolan F., Maïbèche-Coisne M. (2017) Expression and Modulation of Neuroligin and Neurexin in the Olfactory Organ of the Cotton Leaf Worm Spodoptera littoralis. Insect Science 24(2): 210-221

Bozzolan F., Durand N., Demondion E., Bourgeois T., Gassias E., Debernard S. (2017) Evidence for a role of estrogen-related receptor in the regulation of male sexual behavior in the moth Agrotis ipsilon. Insect Mol. Biol. 26(4): 403-413

The Fall ArmyWorm International Consortium (2017) Two genomes of highly polyphagous lepidopteran pests (Spodoptera frugiperda, Noctuidae)with different host-plant ranges. Scientific Reports 7(1):11816

Chertemps T., Younus F., Steiner C., Durand N., Coppin C.W., Pandey G., Oakeshott J.G., Maïbèche M. (2015) An antennal carboxylesterase from Drosophila melanogaster, esterase 6, is a candidate odorant-degrading enzyme toward food odorants. Front. Physiol. 6(315)

Bozzolan F., Siaussat D., Maria A., Durand N., Pottier M.A., Chertemps T., Maïbèche-Coisne M. (2014) Antennal UDPglycosyltransferases in a pest insect: diversity and putative function in odorant and xenobiotics clearance. Insect Mol Biol. 23(5):539-549

Bohbot J.B., Durand N.F., Vinyard B.T., Dickens J.C. (2013) Functional Development of the Octenol Response in Aedes aegypti. Front. Physiol. 4(39)

Chertemps T., François A., Durand N., Rosell G., Dekker T., Lucas P., Maïbèche-Coisne M. (2012) A carboxylesterase, Esterase-6, modulates sensory physiological and behavioural response dynamics to pheromone in Drosophila. BMC Biology 10(56)

Chertemps T., Montagné N., Bozzolan F., Maria A., Durand N., Maïbèche-Coisne M. (2012) Characterization of maspardin, responsible for human Mast syndrome, in an insect species and analysis of its evolution in metazoans. Naturwissenchaften 99: 537–543

Durand N., Carot-Sans G., Bozzolan F., Rosell G., Siaussat D., Debernard S., Chertemps T., Maïbèche-Coisne M. (2011) Degradation of pheromone and plant volatile components by a same odorant-degrading enzyme in the cotton leafworm, Spodoptera littoralis. PLoS One

6(12): e29147

Durand N., Carot-Sans G., Chertemps T., Montagné N., Jacquin-Joly E., Debernard S., Maïbèche-Coisne M. (2010). A diversity of putative carboxylesterases are expressed in the antennae of the noctuid moth Spodoptera littoralis. Insect Mol Biol. 19(1): 87-97

Durand N., Carot-Sans G., Chertemps T., Bozzolan F., Party V., Renou M., Debernard S., Rosell G., Maïbèche-Coisne M. (2010) Characterization of an antennal carboxylesterase from the pest moth Spodoptera littoralis degrading host plant volatile. PLoS One 5(11): e15026

Branco M., Boavida C., Durand N., Carlos J., Mendel Z. (2009). Presence of the Eucalyptus gall wasp Ophelimus maskelli and its parasitoid Closterocerus chamaeleon in Portugal: First record, geographic distribution and host preference.Phytoparasitica 37(1): 51-54