Post-doctoral Research Fellow Position for Production of Recombinant Proteins

The research groups EDYSAN (Ecology and Dynamics of Anthropized Systems) and LPCM (Laboratory of Cellular and Molecular Physiology) at the University of Picardie Jules Verne (Amiens, Region “Les Hauts de France”, Fr.) are inviting applications for a Post-doc research position for producing recombinant proteins. The consortium is working on biological toxins, identified from hymenopteran venom, that are involved in human cell regulation. The PARAVETOX project (funded by the Regional Council of the Hauts de France : project Start- AIRR) is willing to value those proteins present in the venoms of hymenopteran parasitoids.

The challenge

The task of the Post-doc fellow will be to produce a recombinant protein by optimizing upstream and donwstream processing in different prokaryotic and eukaryotic cell systems.

The project

The aim of the PARAVETOX project is the design of protocols allowing the production of biomolecules extracted from hymenopteran insect venoms, and the development of techniques for gene cloning and expression in view of molecule applications in the long term. The PARAVETOX project is based on a multidisciplinary approach dedicated to the exploitation of biologically active molecules that potentially have therapeutic effects.

The profile

Applicants for this position should have a strong background in molecular biology and recombinant protein production. She/he must have a PhD obtained within the last 3 years in either life sciences, biology and/or molecular biology. Some experience with mammal cell culture will be beneficial to the applicant.

The context

The post-doc will be based at the Science Department of the University of Picardie Jules Verne. She/he will work under the supervision of Dr. Anas Cherqui (Associated Professor, EDYSAN) and Dr. Halima Ahidouch-Ouadid (Professor, LPCM). The LPCM and EDYSAN laboratories, as well as the CRRBM platform (Center for Regional Resources in Molecular Biology), will provide all material and equipment necessary for the different experimental stages and completion of the project. LPCM will be particularly involved in assisting the part of the project on human cell tests. Cloning and expression of recombinant proteins in heterologous systems will be performed with the CRRBM. The starting date of this project is early 2019. The application deadline is January 15th, 2019. The salary offered for this Post-doc position is 2000 euros per month (free of tax). The biomolecules identified during this Post-doc position will be subject to patent applications.

The application

A cover letter (written in French or in English) showing your interest, a short CV with a list of publications and the names of 2 references should be sent by email in a single combined pdf-file to:
Dr. Anas Cherqui ; anas.cherqui@u-picardie.fr
Pr. Halima Ahidouch-Ouadid ; halima.ahidouch-ouadid@u-picardie.fr