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Tel : 03 22 82 88 12
Fax : 03 22 82 75 60
Nos travaux portent sur la valorisation des substrats issus de la biomass et plus spécifiquement la valorisation des sucres et de leurs dérivés. Je m'intéresse particulièrement à la découverte de nouveaux outils, de nouvelles réactions, pour faciliter la transformation de ces molécules vers des produits à plus haute valeur ajoutée. Actuellement nous développons deux axes:
Using NMR to Dissect the Chemical Space and O-Sulfation Effects within the O- and S-Glycoside Analogues of Heparan Sulfate |
Synthesis of novel S- and O-disaccharide analogs of heparan sulfate for heparanase inhibition |
Metal-free hydroxy and aminocyanation of furanos-3-uloses |
Ring-Opening of Cyclodextrins: An Efficient Route to Pure Maltohexa-, Hepta-, and Octaoses |
Design, Synthesis and Antibacterial Activity Evaluation of 4,5-Diphenyl-1H-Imidazoles Derivatives |
Effects of CoCl2 on the regioselective tosylation of oligosaccharides |
Synthesis and interfacial properties of new 6-sulfate sugar-based anionic surfactants |
Physicochemical, foaming and biological properties of lowly irritant anionic sugar-based surfactants |
Synthesis of multivalent S-glycosides analogs of a heparan sulfate sequence |
Preparation of nucleoside derivative carrying an isothiazole or oxathiole cycle with an antiproliferative activity |
Metal-free oxidative esterification of benzylated monosaccharides |
Water-mediated synthesis of disubstituted 5-aminopyrimidines from vinyl azides under microwave irradiation |
Measurement of cytotoxicity and irritancy potential of sugar-based surfactants on skin-related 3D models |
Physico-chemical properties and cytotoxic effects of sugar-based surfactants: Impact of structural variations |
Reactivity of D-fructose and D-xylose in acidic media in homogeneous phases |
Metal-Free Oxidative Lactonization of Carbohydrates Using Molecular Iodine |
Metal-Free, Diamine-Mediated, Oxidative Monoamidation of Benzylated Carbohydrates |
Synthesis of glycosylamines and glyconamides using molecular iodine |
Metal-free oxidative lactonization of carbohydrates using molecular iodine |
Synthesis of 1,5-di-C-alkyl 1,5-iminoxylitols related to 1-deoxynojirimycin |
Biological study of a somatostatin mimetic based on the 1-deoxynojrimycin scaffold |