Maître de Conférences
Mail : vincent.moreau@u-picardie.fr
Tel : 03 22 82 76 60
Fax : 03 22 82 75 62
C.V.
Membre de l'équipe SUPRA
Description des travaux de recherche
Trois thèmes sont actuellement développés :
- La synthèse de cyclodextrines glycosylées dans le but d'obtenir de nouveaux « véhicules moléculaires » pouvant être utilisés pour la vectorisation de principes actifs.
- L'obtention par modification chimique d'oligosaccharides amphiphiles.
- La synthèse de fragments oligosaccharidiques de polysaccharides de surface de bactéries.
Publications
- Direct synthesis of novel amphiphilic cyclodextrin.
D. GALLOIS-MONTBRUN, N. THIEBAULT, V. MOREAU, G. LE BAS, J.-C. ARCHAMBAULT, S. LESIEUR, F. DJEDAINI-PILARD.
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2007, 57(1-4), 131-135.
- Oligosaccharide tagged β-cyclodextrins: synthesis and biological affinity towards Concanavalin A.
N. SMILJANIC, V. MOREAU, D. YOCKOT, J. M. GARCIA FERNÀNDEZ, F. DJEDAINI-PILARD.
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2007, 57(1-4), 9-14.
- Supramolecular control of oligosaccharide-protein interactions: switchable and tunable ligands for concanavalin A based on β-cyclodextrin.
N. SMILJANIC, V. MOREAU, D. YOCKOT, J. M. BENITO, J. M. GARCIA FERNÀNDEZ, F. DJEDAINI-PILARD.
Angewandte Chemie, International Edition, 2006, 45(33), 5465-5468.
- Electrospray ionization mass spectrometry: a key analytical tool for the characterization of regioselectively derivatized maltooligosaccharides obtained starting from natural β-cyclodextrin.
D. LESUR, A. GASSAMA, V. MOREAU, F. DJEDAINI-PILARD, A. BRIQUE, S. PILARD.
Rapid Communications in Mass Spectrometry, 2005, Volume Date 2006, 20(5), 747-754.
- Synthesis of regioselectively and uniformly modified maltoheptaose derivatives from cyclomaltoheptaose precursors.
D. LESUR, A. GASSAMA, V. MOREAU, S. PILARD, F. DJEDAINI-PILARD.
Carbohydrate Research, 2005, 340(6), 1225-1231.
- Regioselective glycosylation of 3,6-unprotected mannoside derivatives: fast access to high-mannose type oligosaccharides.
N. SMILJANIC, S. HALILA, V. MOREAU, F. DJEDAINI-PILARD.
Tetrahedron Letters, 2003, 44(50), 8999-9002.
- Synthesis and characterization of mannosyl mimetic derivatives based on a β-cyclodextrin core.
D. YOCKOT, M. MOREAU, G. DEMAILLY, F. DJEDAINI-PILARD.
Organic & Biomolecular Chemistry, 2003, 1(10), 1810-1818.
- Crystallization of the catalytic domain of Clostridium cellulolyticum CeIF cellulase in the presence of a newly synthesized cellulase inhibitor.
C. REVERBEL-LEROY, G. PARSIEGLA, V. MOREAU, M. JUY, C. TARDIF, H. DRIGUEZ, J.-P. BELAICH, R. HASER.
Acta crystallographica, section d: biological crystallography, 1998, D54(1), 114-118.
- Transglycosidation activity of Bacillus 1,3-1,4-β-D-glucan 4-glucanohydrolases. Enzymic preparation of alternate 1,3-1,4-β-D-gluco-oligosaccharides.
J.-L. VILADOT, V. MOREAU, A. PLANAS, H. DRIGUEZ
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry, 1997, (16), 2383-2387.
- Synthesis of methyl 4-thio-β-cellobioside. A reinvestigation.
V. MOREAU, J. C. NORRILD, H. DRIGUEZ.
Carbohydrate Research, 1997, 300(3), 271-277.
- Design and chemoenzymic preparation of thio oligosaccharide as inhibitors of 1,3:1,4-β-D-glucanases.
V. MOREAU, J.-L. VILADOT, E. SAMAIN, A. PLANAS, H. DRIGUEZ.
Bioorganic & Medicinal Chemistry, 1996, 4(11), 1849-1855.
- Enzymic synthesis of hemithiocellodextrins.
V. MOREAU, H. DRIGUEZ.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry, 1996, (6), 525-7.
- Phosphorolytic synthesis of cellodextrins.
E. SAMAIN, C. LANCELON-PIN, F. FERIGO, V. MOREAU, H. CHANZY, A. HEYRAUD, H. DRIGUEZ.
Carbohydrate Research, 1995, 271(2), 217-26.