
Maître de Conférences
Mail :sylvestre.toumieux@u-picardie.fr
Tél : 03 22 82 75 69
Fax : 03 22 82 75 60
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Synthesis of the gymnodimine tetrahydrofuran core through a Ueno-Stork radical cyclization.
S. Toumieux, R. Beniazza, V. Desvergnes, R. Araoz, J. Molgo, Y. Landais, Org. Biomol. Chem., 2011, 9, 3726–3732.
Constrained Peptidomimetics Reveal Detailed Geometric Requirements of Covalent Prolyl Oligopeptidase Inhibitors J. Lawandi, S. Toumieux, V. Seyer, P. Campbell, S. Thielges, L. Juillerat-Jeanneret, N. Moitessier, J. Med. Chem., 2009, 52, 6672-6684.
Iterative multifunctionalization of unactivated C-H bonds in piperidines by way of intramolecular Rh(II)-catalyzed aminations S. Toumieux, P. Compain, O. R. Martin, J. Org. Chem., 2008, 73, 2155-2162.
Intramolecular Rhodium-catalyzed Activation of α-Amino C-H Bonds: Decisive Influence of Conformational Factors in the Synthesis of Bicyclic Aminals from N-Sulfamoyloxyacetyl Azacycloalkanes M. S. T. Morin, S. Toumieux, P. Compain, S. Peyrat, J. Kalinowska-Tluscik, Tetrahedron Lett.,2007, 48, 8531-8535.
Synthesis of 4-O-glycosylated 1-deoxynojirimycin derivatives as disaccharide mimics-based inhibitors of human béta-glucocerebrosidase C. Boucheron, S. Toumieux, P. Compain, O. R. Martin, K. Ikeda, N. Asano, Carbohydr. Res., 2007, 1960-1965.
New aspects of catalytic intramolecular C-H amination: Unexpected formation of a seven-membered ring in nitrogen-containing systems S. Toumieux, P. Compain, O. R. Martin, M. Selkti, Organic Letters, 2006, 8, 4493-4496.
Intramolecular Metal-catalyzed Amination of Pseudo-anomeric C–H Bonds
S. Toumieux, P. Compain, O. R. Martin, Tetrahedron Lett., 2005, 46, 4731–4735.
Tables of iminosugars, their biological activities and their potential as therapeutic agents.
P. Compain, V. Desvergnes, V. Liautard, C. Pillard, S. Toumieux, Iminosugars: from Synthesis to Therapeutic Applications, (P. Compain, O. R. Martin, Eds.), Wiley-VCH, Weinheim, 2007, Chap. 14, 327-455.
Catalytic Intramolecular C-H Aminations: A powerful tool for the synthesis of various heterocyclic systems.
P. Compain, S. Toumieux, Targets in Heterocyclic systems – Chemistry and Properties, 2007, 11, 338-364.